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Dr. Amanda Evans

Assistant Professor Bioorganic Chemistry

Dr. Amanda Evans

Research interests include immobilized whole cell engineered enzyme approaches for continuous bioprocessing ("Enz-Flow"), circularly polarized light for generating tunable molecular chirality, and microfluidic syntheses and analytics in microgravity environments. 

 

Office: MH-582E
Phone: (657) 278-2505
Lab: DBH-164N, 164S
Phone: (657) 278-8583
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.


Courses Taught

  • CHEM 301A, CHEM 301B Organic Chemistry Lecture
  • CHEM 306A, Organic Chemistry Lab
  • CHEM 115, Introduction to General Chemistry
  • CHEM 505A/B, Graduate Seminar Series/Graduate Presentation Skills

Education

Ph.D. Synthetic Organic Chemistry, King's College, University of Cambridge, Cambridge, UK
"Diastereoselective Desymmertrisation of Cyclic meso-Anhydrides and Derivatisation for Use in Natural Product Synthesis"
Supervisor:  Professor S.V. Ley FRS, CBE.

B.A. Chemsitry and Classical Studies, Magna cum Laude, Honors in Chemistry, Bryn Mawr College, Bryn Mawr, PA, USA


Publications

  • "Neonicotinoids: Systemic Insecticides and Systematic Failures” Kurwadkar, S.T.*; Evans, A.; Bull. Environ. Contam. Toxicol. 2016, DOI: 10.1007/s100128-0161968-3.
  • “Modeling photodegradation kinetics of three systemic neonicotinoids – dinotefuran, imidacloprid and thiomethoxam in aqueous and soil environments” Kurwadkar, S.T.*; Evans, A.; DeWinne, D.; White, P.; Mitchell, F.; Environmental Toxicology and Chemistry, 2016, DOI: 10.1002/etc.3335.
  • “Understanding Photochirogenesis - Solvent- and Supramolecular Effects on Circular Dichroism and Anisotropy Spectroscopy”, Bredehöft, J.H.*; Jones, N.C.; Meinert, C.; Evans, A.C.; Hoffmann, S.V.; Meierhenrich, U.J.; Chirality 2014, 26(8), 373-8; DOI: 10.1002/chir22329.
  • “Photonenergy-controlled Symmetry Breaking with Circularly Polarised Light”, Meinert, C.*; Hoffmann, S.V.; Cassam-Chenaï, P.; Evans, A.C.; Giri, C.; Nahon, L.*; Meierhenrich, U.J.; Angew. Chem. Int. Ed. 2013, 53(1), 210-4. DOI: 10.1002/anie.201307855
  • “Anisotropy Spectroscopy for Chiral Differentiation of Biomolecular Building Blocks”, Evans, A.C.; Jones, N.C.; Meinert, C.; Bredehöft, J.H.; Giri, C.; Goesmann, F.; Hoffmann, S.V.; Meierhenrich, U.J.*; Invited Review Top. Curr. Chem. Springer, Berlin; 2013, 341, 271-99; DOI: 10.1007/128_2013_442.
  • “G-Quadruplex and i-Motif Formation Affect Proximal Duplex Stability”, König, S.L.B.; Sigel, R.K.O., Huppert, J.L.; Evans, A.C.*; Nucl. Acids Res. 2013, 41(15), 7453-61; DOI: 10.1093/nar/gkt476.
  • “Synthesis and Chirality of Amino Acids under Interstellar Conditions”, Giri, C.; Goesmann, F.; Meinert, C.; Evans, A.C.; Meierhenrich, U.*; Invited Review Top. Curr. Chem., 2013, 333, 41-82; Springer, Berlin; DOI: 10.1007/128_2012_367.
  • • “Photochemical Synthesis, Chirality and Detection of Amino Acids in Interstellar Ice Analogues and Comets”, Evans, A.C.; Meinert, C.; Giri, C.; Goesmann, F.; Meierhenrich, U.*; Chem. Soc. Rev., Advanced Article; 2012, 41, 5447-5458, DOI: 10.1039/C2CS35051C.
  • • “The Use of Nucleophilic Oligonucleotides to Carry Out Acyl-Transfer Reactions Under Physiological Conditions”, McKee, M.; Evans, A.C.; Gerrard, S.R.; Stulz, E.*; O'Reilly, R.K.*; Turberfield, A.*; Org. Biomol. Chem., 2011, 9, 1661-1666, DOI: 10.1039/C0OB00753F.
  • “Organocatalytic Tunable Amino Acid Polymers Prepared by Controlled Radical Polymerisation”, Evans, A.C.; Lu, A.; Ondeck, C.; Longbottom, D.A.*; O’Reilly, R.K.*; Macromolecules, 2010, 43(15), 6374-6380, DOI: 10.1021/ma1008447.
  • • “Seven Essential Questions on G-Quadruplexes”, König, S.L.B.; Evans, A.C.; Huppert, J.L.*; Biomolecular Concepts, 2010, 1(2), 197-213, DOI: 10.1515/BMC.2010.011.
  • • "Functional and Tuneable Polymers Prepared by RAFT Polymerisation of Polystyrenes”, Evans, A.C.; Skey, J.; Wright, M.; Xu, W.-J.; Ondeck, C.; Longbottom, D.A.*; O’Reilly, R.K.*; J. Polym. Sci. Part A: Polym. Chem., 2009, 47 (24), 6814-6826, DOI: 10.1002/pola.23721.
  • “Highly Diastereoselective Desymmetrisation of Mono-, Bi- and Tricyclic meso-Anhydrides Using a Weinreb Amide Chiral Auxiliary and Application to Natural Product Synthesis”. Evans, A.C.; Longbottom, D.A.; Matsuoka, M.; Davies, J.E.; Turner, R.; Franckevicius, V.; Ley, S.V.* Org. Biomol. Chem., 2009, 7, 747-760, DOI: 10.1039/b813494d.
  • • “Highly Diastereoselective Desymmetrisation of Cyclic meso-Anhydrides and Derivatisation to Mono-protected 1,4-Diols”. Evans, A.C.; Longbottom, D.A.; Matsuoka, M.; Ley, S.V.* Synlett. 2005, 646-648; DOI: 10.1055/s-2005-862393.
  • • “Phenacenes: A Family of Graphite Ribbons. 2. Syntheses of some [7]Phenacenes and an [11]Phenacene by Stilbene-like Photocyclizations”. Mallory, F.B.*; Butler, K.B.; Evans, A.C.; Brondyke, E.J.; Mallory, C.W.; Yang, C.; Ellenstein, A.J. J. Am. Chem. Soc. 1997, 119, 2119-2124; DOI: 10.1021/ja963418.
  • • “Phenacenes: A Family of Graphite Ribbons. 1. Syntheses of some [7]Phenacenes by Stilbene-like Photocyclizations”. Mallory, F.B.*; Butler, K.E.; Evans, A.C.; Mallory, C.W. Tetrahedron Lett. 1996, 40, 7173-7176; DOI: 10.1016/0040-4039(96)01618-8.

Grants

  • Awarded beamtime at ISA, Aarhus University – PI (2017 & 2016)
  • American Chemical Society Green Chemistry Institute Pharmaceutical Roundtable Research Grant – PI (2016-2018)
  • CSUPERB New Investigator Grant – PI (2015-2017)
  • Jean-Dreyfus Boissevain Lectureship - CoPI (2014-2016)
  • CSUF Department of Chemistry & Biochemistry Start-up Grant - PI (2014-2016)
  • Royal Society of Chemistry JWT Jones Travelling Fellowship (France/Denmark) (2012-2013)
  • Fulbright Student Scholar Fellowship (Germany) (1997-1998)

Journal Reviewer

  • Molecules
  • Journal of Flow Chemistry
  • Synlett
  • Biochemistry

Grant Reviewer

  • Agence Nationale de la Recherche (ANR)
  • National Science Foundation (NSF)
  • California State University (CSUPERB)

Editorial Boards

    • Editor for the Thematic Series for the Bozen Symposium 2016, Beilstein Institute

Session Chair

    • Beilstein Bozen Symposium, Prien, Germany 2016
    • American Chemical Society Regional Meeting, San Marcos, USA, 2015
    • American Chemical Society National Meeting, San Francisco, USA, 2017